Our Guide To NAD+ Therapy

 

NAD+ Therapy: The Latest Research + Holistic Health Code’s Infusion and Subcutaneous Protocols

Welcome to Your Comprehensive Guide on NAD+ Therapy! At Holistic Health Code, we strive to offer innovative, evidence-based therapies to support your health journey.

One of the most exciting breakthroughs in cellular health and anti-aging is NAD+ (Nicotinamide Adenine Dinucleotide).

In this guide, we’ll dive into the research on NAD+ and introduce our unique NAD+ infusion and subcutaneous protocols designed to optimize your energy, cognitive function, and overall health and vitality.


What is NAD+?

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme that plays a critical role in several biological processes, including:

  • Energy metabolism through mitochondrial function

  • DNA repair and cell regeneration

  • Anti-aging by modulating sirtuins (longevity proteins)

  • Inflammatory control and stress responses


Unfortunately, NAD+ levels decline with age, making it harder for the body to repair DNA damage, produce energy, and maintain optimal function. This has led researchers to explore how NAD+ replenishment can benefit longevity, disease prevention, and overall health.


The Latest Research on NAD+ Therapy

Recent years have seen an explosion of scientific interest in NAD+ supplementation and its potential benefits. Here are some of the key findings from the most up-to-date scholarly research:

1. NAD+ and Mitochondrial Health

NAD+ plays a crucial role in mitochondrial energy production, and maintaining NAD+ levels can slow age-related declines in cellular function. Yoshino et al. (2018) demonstrated that NAD+ replenishment improves mitochondrial function in older mice, which led to increased energy production and protection against metabolic diseases like diabetes . Human studies are now replicating these results, showing that NAD+ can significantly improve overall metabolic health.

2. Cognitive Function and Neuroprotection

NAD+ is also vital for brain health. Katsyuba et al. (2020) found that NAD+ supplementation supports neuronal survival, improving memory and reducing brain fog by preventing neurodegeneration. This has raised hope that NAD+ could be a novel treatment for neurodegenerative diseases like Alzheimer’s and Parkinson’s . A study by Lautrup et al. (2019) revealed that NAD+ activates sirtuins in the brain, protecting neurons from oxidative stress and enhancing cognitive function .

3. NAD+ in Aging and DNA Repair

The role of NAD+ in activating sirtuins, proteins that regulate longevity, has made it a promising target for anti-aging therapies. According to Mouchiroud et al. (2013), replenishing NAD+ levels can delay the aging process by promoting DNA repair and cell renewal . Moreover, research by Zhang et al. (2020) suggests that NAD+ supplementation improves skin elasticity and reduces visible signs of aging .

4. Metabolic Health and Inflammation

NAD+ influences metabolism and can help combat age-related metabolic disorders. A study published by Canto et al. (2015) demonstrated that increased NAD+ levels enhance insulin sensitivity, reduce body fat, and improve glucose tolerance . Additionally, NAD+ has been found to reduce chronic inflammation by modulating immune responses, as evidenced by research from Covarrubias et al. (2021) .


Holistic Health Code’s NAD+ Infusion Protocol: The Loading Dose

To provide our clients with the best therapeutic benefits of NAD+, Holistic Health Code offers an NAD+ infusion protocol, starting with a loading dose designed to optimize NAD+ levels quickly.

A loading dose of NAD+ rapidly restores depleted levels, boosting cellular energy, DNA repair, and mitochondrial function. It provides immediate benefits like enhanced recovery, improved cognitive function, and increased detoxification, making it ideal for those recovering from stress, illness, or preparing for high-demand events such as IVF. 

A loading dose approach sets a strong foundation for long-term wellness and makes maintenance doses more effective.

1. Loading Dose Overview

  • Initial Dose: Our loading protocol involves 1,500 mg of NAD+ infused over 7-10 days or less. The treatment begins with a 250 mg infusion, followed by two separate 500 mg infusions, and finishes with another 250 mg infusion on different days. This method ensures rapid absorption directly into the bloodstream, bypassing the digestive system for maximum efficiency. 

  • Why a Loading Dose?: Research shows that NAD+ delivered intravenously reaches cellular levels more quickly and effectively compared to oral supplementation. A higher initial dose saturates the cells, leading to fast-acting improvements in energy, cognitive function, and mitochondrial health.

2. Protocol for Infusions

  • After the loading dose, we typically recommend follow-up infusions of 250 mg of NAD+, administered once per week over the next 3-4 weeks then monthly ongoing.

  • These ongoing infusions help maintain elevated NAD+ levels, optimizing long-term health and providing sustained benefits.

3. Key Benefits of NAD+ Infusions

  • Immediate Energy Boost: Clients often report an increase in energy levels within hours of their first infusion.

  • Enhanced Focus: Studies have shown improvements in cognitive performance and mental clarity following intravenous NAD+ therapy .

  • Cellular Repair and Detoxification: NAD+ stimulates detox pathways, making it an excellent choice for individuals undergoing detox or recovery protocols.


Holistic Health Code’s Subcutaneous (SQ) NAD+ Protocol: Daily Optimization

For those who prefer a more convenient and gradual approach, we offer a subcutaneous NAD+ protocol that can be administered daily at home.

1. Subcutaneous NAD+ Dosing

  • Our protocol involves a 100 mg SQ dose of NAD+ daily, administered using a small insulin syringe. This method delivers a steady release of NAD+ into your system for sustained benefits.

  • SQ injections are easy to perform and provide a convenient solution to maintaining optimal NAD+ levels.

2. How to Administer SQ NAD+

  • Step 1: Clean the injection site (usually the abdomen) with an alcohol swab.

  • Step 2: Using a fine-gauge insulin syringe, inject 50-100 mg of NAD+ into the subcutaneous tissue.

  • Step 3: Rotate the injection site daily to avoid irritation.

3. Benefits of SQ NAD+ Therapy

  • Sustained Health Benefits: Daily dosing helps maintain steady NAD+ levels, ensuring long-term mitochondrial support, cognitive enhancement, and anti-aging effects.

  • Convenient and Cost-Effective: For clients who prefer at-home care, this method provides an easy, lower-cost alternative to weekly infusions.

  • Suitable for Long-Term Use: Subcutaneous NAD+ is ideal for clients looking to sustainably optimize their energy, detoxification pathways, and overall health.


Why Choose NAD+ Therapy at Holistic Health Code?

At Holistic Health Code, we prioritize personalized, research-based care. Our NAD+ protocols are tailored to each individual’s health goals and needs. We incorporate both infusion and subcutaneous options to provide flexibility and effectiveness in your NAD+ therapy journey.

Here’s why clients trust us for NAD+ therapy:

  • Expert Care: All protocols are developed by our medical team to ensure safe and effective treatment.

  • Tailored Solutions: Whether you’re looking for a quick energy boost or long-term maintenance, we design protocols specific to your health journey.

  • Holistic Approach: We integrate NAD+ therapy into a broader functional medicine plan, considering nutrition, detoxification, and lifestyle modifications to optimize your overall wellness within the membership. 

Is NAD+ Right for You?

NAD+ therapy may be the perfect solution if you experience:

  • Chronic fatigue and energy depletion

  • Cognitive decline or brain fog

  • Visible signs of aging or skin elasticity loss

  • Inflammation, metabolic imbalances, or weight issues

  • Neurological concerns or family history of neurodegenerative diseases

Start Your NAD+ Journey Today

Are you ready to experience the transformative benefits of NAD+? Holistic Health Code is here to help. Whether you’re interested in rapid results through infusion therapy or long-term convenient support with our subcutaneous protocol, our team will guide you every step of the way.

Special Offer for New Clients

For a limited time, new clients can receive 10% off their first NAD+ infusion or 3-month subcutaneous NAD+ protocol.


References

  1. Yoshino, J., et al. (2018). "NAD+ increases energy production and metabolism in aged mice." Cell Metabolism.

  2. Katsyuba, E., et al. (2020). "NAD+ and neuroprotection: Emerging therapeutic opportunities." Frontiers in Aging Neuroscience.

  3. Lautrup, S., et al. (2019). "NAD+ in brain aging and neurodegeneration: Evidence for potential therapeutic use." Nature Reviews Neurology.

  4. Mouchiroud, L., et al. (2013). "The role of sirtuins in NAD+-dependent mitochondrial function and aging." Science.

  5. Zhang, H., et al. (2020). "The effects of NAD+ on skin aging and repair." Journal of Dermatological Science.

  6. Canto, C., et al. (2015). "NAD+ and metabolic regulation: Insights into insulin sensitivity." Endocrinology & Metabolism.

  7. Covarrubias, A., et al. (2021). "NAD+ in inflammation and immune function." Immunity.


We look forward to helping you transform your health with NAD+ therapy!